The DNA sample is collected on four buccal swabs, rubbed inside the mouth against the cheek for 15 seconds.
Individuals who carry the Factor V Leiden mutation have a 3- to 8-fold increased risk as heterozygotes and a greater than 10-fold increased risk as homozygotes. Individuals who carry the F2 prothrombin mutation have a 2- to 5-fold increased risk as heterozygotes and up to a 10-fold increased risk as homozygotes. Individuals who carry two [...]
No, not everyone who carries one or more of the thrombosis risk alleles will suffer from a blood clot. Although each of these mutations increase the risk of thrombophilia to varying degrees there are many individuals that have these alleles and never experience thrombosis.
The thrombotic risk DNA panel offered by Genetrace includes the analysis of mutations in three genes – F5 (Factor V Leiden 1691G>A mutation), F2 prothrombin (Prothrombin 20210G>A mutation) and MTHFR (677C>T and 1298A>C mutations).
Pulmonary embolism occurs when a blood clot breaks loose and travels to the lungs obstructing a pulmonary artery.
Deep vein thrombosis is a blood clot that occurs in on of the deep veins in the body (usually in the legs).
Deep vein thrombosis symptoms include swelling, warmth, pain and redness in the affected area. Pulmonary embolism symptoms include sudden shortness of breath, chest pain, increased heart rate and coughing up blood.
A group of conditions where there is a higher tendency for blood to form abnormal clots, leading to an increased risk of developing thrombosis.
The obstruction of blood flow in the circulatory system due to a blood clot.
You can choose to receive your results report by mail, email or both. The test includes one copy of the results by mail and one copy by email at no charge. The results report is issued immediately once the testing is completed.